Video: Board Prep – Familial Tumor Syndrome, Mystery Case #1

Mystery case review #1 is the first of a series of videos designed to review the variety of brain tumors that arise in the context of a familial tumor syndromes.  Test your knowledge with questions posed to the audience in a quiz like format. In-depth answers are provided for each quiz question. This series is... Continue Reading →

Video: Radiation and Brain Tumors Part 3 – Brain Tumors and Outer Space, featuring Dr Sandeep Burma

Part 3 of a three-part series reviewing the effects of radiation on the brain. Join in on this grand finale as we review brain tumor development in a pilot who had logged many hours flying aircraft at high altitudes.  High altitude pilots at the edge of the Earth's protective atmospheric shield, and astronauts just beyond it,... Continue Reading →

Dura Metastasis: Hepatocellular Carcinoma

The most common tumors found in the central nervous system and dura (i.e. the dense fibrous covering that envelops the brain) are those that have traveled from other body sites in a process called metastasis.  Depicted here is hepatocellular carcinoma (HCC), a cancer of liver cells, that has metastasized to the dura overlying the anterior pole of the right frontal lobe. Microscopically, the neoplastic liver... Continue Reading →

Severe Jaundice of the Brain

Not a trick of the eyes.  This brain with a pronounced green discoloration belonged to an adult with marked jaundice due to acute and severe liver disease. Jaundice occurs when the blood carries higher than normal levels of bilirubin, a substance that is usually processed by the liver into bile which is then eliminated via the stool and urine. Liver disease... Continue Reading →

Mengioma: Vascular Changes and Prognosis

Meningiomas, like the one pictured here, typically show whorling architectural pattern and nuclear pseduoinclusions.  The vast majority of meningiomas are low grade (WHO Grade 1) dura-based tumors with good prognosis following complete resection.  However, recent studies have suggested that endothelial cell hypertrophy and/or microvascular proliferation in an otherwise typical meningioma are correlated with shorter progression free... Continue Reading →

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