Dura Metastasis: Hepatocellular Carcinoma

The most common tumors found in the central nervous system and dura (i.e. the dense fibrous covering that envelops the brain) are those that have traveled from other body sites in a process called metastasis.  Depicted here is hepatocellular carcinoma (HCC), a cancer of liver cells, that has metastasized to the dura overlying the anterior pole of the right frontal lobe. Microscopically, the neoplastic liver... Continue Reading →

Advertisements

Severe Jaundice of the Brain

Not a trick of the eyes.  This brain with a pronounced green discoloration belonged to an adult with marked jaundice due to acute and severe liver disease. Jaundice occurs when the blood carries higher than normal levels of bilirubin, a substance that is usually processed by the liver into bile which is then eliminated via the stool and urine. Liver disease... Continue Reading →

Mengioma: Vascular Changes and Prognosis

Meningiomas, like the one pictured here, typically show whorling architectural pattern and nuclear pseduoinclusions.  The vast majority of meningiomas are low grade (WHO Grade 1) dura-based tumors with good prognosis following complete resection.  However, recent studies have suggested that endothelial cell hypertrophy and/or microvascular proliferation in an otherwise typical meningioma are correlated with shorter progression free... Continue Reading →

Powered by WordPress.com.

Up ↑