A forum dedicated to the expansion in neuropathology knowledge for students and practitioners alike.
Located between the bony vertebrae of the spinal column, the vertebral disks act as cushions and shock absorbers to allow for freedom of movement of the spine. Activities that increase pressure in the lower back, such as repeatedly lifting heavy objects while bending at the waist, may cause the inner gel-like substance (called the center nucleus) of a... Continue Reading →
The massive intraparenchymal hemorrhage depicted in the autopsy specimen of a 60-year-old male patient is the result of hypertensive vasculopathy. Bleeding originated in penetrating vessels of the basal ganglia and extended into adjacent cerebral structures. The blood acts as a space-occupying lesion, resulting in uncal and subfalcine herniation with associated tissue destruction.
This elderly patient complaining of headache was diagnosed with glioblastoma following biopsy of the heterogeneous, ring-enhancing lesion in the right temporal lobe. Mass effect caused by the space-occupying tumor has pushed the ipsilateral cingulate gyrus under the falx cerebri, resulting in a subfalcine herniation.
Adventures in Neuropathology 