Video: Board Prep – Familial Tumor Syndrome, Mystery Case #3

Mystery case review #3 is one of a series of videos designed to review the variety of brain tumors that arise in the context of a familial tumor syndromes. Test your knowledge with questions posed to the audience in a quiz like format. In-depth answers are provided for each quiz question. This series is perfect... Continue Reading →

Video: Normal Neuro Anatomy: Coronal Section of the Brain Through the Anterior Commissure

Take an anatomy tour through a coronal section of the normal brain at the level of the anterior commisure.  Join me as I review the major neuroanatomical structures of the normal brain, touching on structures that are important to normal functioning and also key players in certain disease processes.     https://youtu.be/lwF0AySb0c0

Resorption of Embolic Material in Arteriovenous Malformation (AVM)

Vascular brain lesions have increased risk of intracranial bleeding and, therefore, present a challenge to neurosurgeons attempting surgical resection.  Such tumors may first be embolized prior to surgical excision in order to reduce the risk of bleeding.  Onyx, an ethylene vinyl alcohol copolymer, is one of many embolic agents available to accomplish this task.  Onyx has... Continue Reading →

Hippocampal Atrophy

The hippocampus is critical to learning and memory.  Patients with hippocampal atrophy often have difficulty with declarative memory (i.e. remembering facts, names, events, etc.) and making new memories. Hippocampal atrophy can be seen a variety of disease processes, including epilepsy and neurodegenerative disease. Note how atrophy in this elderly patient, who had memory difficulties prior to... Continue Reading →

Periventricular Leukomalacia (PVL)

Periventricular Leukomalacia (PVL) is a type of brain damage that affects fetuses and premature babies. At this stage of brain  development, the white matter surrounding the ventricles is particularly vulnerable to hypoxic (lack of oxygen) or ischemic (lack of blood flow) injury for a variety of reasons, including high metabolic demand in a location that... Continue Reading →

Brain Eating Amoeba

Naegleria fowleri, better known as "brain-eating amoeba", is a free-living amoeba that is a major cause of a rare brain infection called Primary Amebic Meningoencephalitis, which typically affects young people with a history of swimming in warm fresh water such as a lake or stream. After entering the nose and crawling up the olfactory nerves... Continue Reading →

Malignant Meningitis

The brain is surrounded by several layers of protective coverings collectively called meninges.  The semi-translucent innermost layers, called the leptomeninges, form a "shrink-wrap" around the brain that allows for easy flow of cerebrospinal fluid (CSF) along the outer surface of central nervous system structures. Unfortunately, it also allows for easy spread of neoplastic cells.  The image shows the inferior aspect... Continue Reading →

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