A forum dedicated to the expansion in neuropathology knowledge for students and practitioners alike.
Histopathological diagnosis of Peripheral Neuroblastic Tumors explained (i.e. Neuroblastoma, Ganglioneuroblastoma, and Ganglioneuroma), with an example review of Ganglioneuroma. https://youtu.be/w9FEXK8tvJg
Demyelinating lesions, such as those found in multiple sclerosis, typically contain numerous macrophages with abundant myelin debris filling the cytoplasm. Additionally, atypical and granular mitoses can be seen in demyelinating lesions, though they can also occur in gliomas. Follow us on Facebook, Instagram, and YouTube: Adventures in Neuropathology
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Hemorrhages and hematomas in the Central Nervous system - A narrative of microscopic features. https://www.youtube.com/watch?v=MCx1DFjANzU&feature=youtu.be Follow us on Facebook, Instagram, and YouTube: Adventures in Neuropathology
This cystic and solid suprasellar mass, seen on this brain cut in the coronal plane, represents the classic gross appearance of a craniopharyngioma with typical focal yellow calcifications. The solid parts on gross examination correlate with enhancing regions on MRI while the cystic regions characteristically contain "machine oil"-like fluid, which is not appreciated in this... Continue Reading →
A review of common gross findings of acute traumatic brain injury (TBI), including a discussion of herniation types and contusional patterns. https://www.youtube.com/watch?v=vnPdJ77khgo&t=333s
Psammoma bodies, lamellated purple concretions composed of calcium and other ions, are commonly found in meningiomas and are particularly numerous in the psammomatous variant of meningioma, pictured here. Psammomatous meningiomas are low grade (WHO grade I) tumors that often have a gritty texture on gross evaluation due to increased numbers of psammoma bodies and dystrophic calcification often necessitating... Continue Reading →
Although meningiomas are classically dura-based lesions, they can also arise in the choroid plexus and, thus, must be considered in the differential diagnosis for intraventricular lesions. This intraventricular meningioma, shown here, is growing underneath normal choroid plexus epithelium.
Ependymomas are glial tumors that commonly harbor perivascular pseudo-rosettes, seen here, characterized by radially arranged tumor cells around a blood vessel core. https://youtu.be/UXDIYV_yMro
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