A forum dedicated to the expansion in neuropathology knowledge for students and practitioners alike.
Histopathological diagnosis of Peripheral Neuroblastic Tumors explained (i.e. Neuroblastoma, Ganglioneuroblastoma, and Ganglioneuroma), with an example review of Ganglioneuroma. https://youtu.be/w9FEXK8tvJg
Diffuse axonal injury: Trauma that is strong enough to break long slender blood vessels is usually strong enough to break long delicate axons, too. Therefore, the presence of gross microhemorrhages in long white matter tracts, such as the corpus callosum, strongly suggests that diffuse axonal injury will be seen on microscopic evaluation of the axons comprising these white matter tracts. The image shows... Continue Reading →
Demyelinating lesions, such as those found in multiple sclerosis, typically contain numerous macrophages with abundant myelin debris filling the cytoplasm. Additionally, atypical and granular mitoses can be seen in demyelinating lesions, though they can also occur in gliomas. Follow us on Facebook, Instagram, and YouTube: Adventures in Neuropathology
https://youtu.be/YlKgPHM3YzY Follow us on Facebook, Instagram, and YouTube: Adventures in Neuropathology
https://youtu.be/iQ1Be_0IpJM Follow us on Facebook, Instagram, and YouTube: Adventures in Neuropathology
Hemorrhages and hematomas in the Central Nervous system - A narrative of microscopic features. https://www.youtube.com/watch?v=MCx1DFjANzU&feature=youtu.be Follow us on Facebook, Instagram, and YouTube: Adventures in Neuropathology
This cystic and solid suprasellar mass, seen on this brain cut in the coronal plane, represents the classic gross appearance of a craniopharyngioma with typical focal yellow calcifications. The solid parts on gross examination correlate with enhancing regions on MRI while the cystic regions characteristically contain "machine oil"-like fluid, which is not appreciated in this... Continue Reading →
A review of common gross findings of acute traumatic brain injury (TBI), including a discussion of herniation types and contusional patterns. https://www.youtube.com/watch?v=vnPdJ77khgo&t=333s
Psammoma bodies, lamellated purple concretions composed of calcium and other ions, are commonly found in meningiomas and are particularly numerous in the psammomatous variant of meningioma, pictured here. Psammomatous meningiomas are low grade (WHO grade I) tumors that often have a gritty texture on gross evaluation due to increased numbers of psammoma bodies and dystrophic calcification often necessitating... Continue Reading →
Metastatic cancers (i.e. cancers that originate somewhere else and travel to the brain usually via the bloodstream) can occur singly or, as pictured here, as multiple lesions. Sometimes brain metastases represent the initial clue that the person has cancer somewhere else in the body, as was the case for this patient who was found to have three enhancing cerebral lesions... Continue Reading →
Adventures in Neuropathology 