Secretory Meningioma: A unique Meningioma variant

The secretory subtype of meningioma (pictured here) is just one of many variants of meningioma, a usually histologically benign tumor that arises from the meninges (i.e. the outer coverings overlying the brain) and often contains concentrically-layered calcifications called psammoma bodies.  The secretory variant can be suspected on imaging by the exuberant edema often seen in the adjacent brain tissue.  Microscopically,... Continue Reading →

Psammoma bodies in a psammomatous variant of meningioma.

Psammoma bodies, lamellated purple concretions composed of calcium and other ions, are commonly found in meningiomas and are particularly numerous in the psammomatous variant of meningioma, pictured here.  Psammomatous meningiomas are low grade (WHO grade I) tumors that often have a gritty texture on gross evaluation due to increased numbers of psammoma bodies and dystrophic calcification often necessitating... Continue Reading →

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