The cerebral hemispheres are supplied with blood via three major arteries: the anterior, middle, and posterior cerebral arteries. This coronal section through the frontal lobes shows hemorrhage involving the vascular territory of which of these three major cerebral arteries? Answer: The cerebral hemispheres are supplied with blood via three major arteries: the anterior, middle, and posterior... Continue Reading →
Brain infarction, or stroke, refers to brain tissue death due to a lack of life-sustaining blood flow to this area. This brain, which belonged to a person with extensive cardiovascular disease, shows a resolving infarction involving the cerebral cortex of the occipital lobe. Microscopically this yellow-brown discolored area is infiltrated by an army of macrophages that slowly removes the dead brain tissue until,... Continue Reading →
The massive intraparenchymal hemorrhage depicted in the autopsy specimen of a 60-year-old male patient is the result of hypertensive vasculopathy. Bleeding originated in penetrating vessels of the basal ganglia and extended into adjacent cerebral structures. The blood acts as a space-occupying lesion, resulting in uncal and subfalcine herniation with associated tissue destruction.