Video: Glioblastoma Histopathologic Diagnosis

A review of the histopathologic diagnosis of the most common primary malignant brain tumor: glioblastoma. https://www.youtube.com/watch?v=3KD6wnMR6Lg&t=74s

July 29, 2018 0

Glioblastomas

Glioblastomas are high grade astrocytomas that often exhibit microvascular proliferation, characterized by atypical hypertrophic and hyperplastic endothelial cells. A mitotic figure within a proliferating endothelial cell is present in the top right corner of the image.

July 8, 2018 0

Glioblastoma with Ring Enhancement (MRI)

This middle aged patient had a heterogeneous lesion with multiple irregular rings of enhancement following contrast administration. Biopsy revealed glioblastoma with microvascular proliferation and necrosis, both of which contain leaky blood vessels that contribute to contrast enhancement on imaging.

July 8, 2018 0

MRI of Glioblastoma with Subfalcine Herniation

This elderly patient complaining of headache was diagnosed with glioblastoma following biopsy of the heterogeneous, ring-enhancing lesion in the right temporal lobe. Mass effect caused by the space-occupying tumor has pushed the ipsilateral cingulate gyrus under the falx cerebri, resulting in a subfalcine herniation.

July 8, 2018 0

Video: Recognizing Vascular Proliferation in Glioblastomas

Short segment on recognizing vascular proliferation in Glioblastomas. https://www.youtube.com/watch?v=UefxKiHxwzo

July 8, 2018 0

Ependymoma

A common histologic finding in ependymomas (shown here) are perivascular pseudo-rosettes characterized by neoplastic ependymal cell nuclei radiating outward from a blood vessel, which creates a pink zone of glial processes immediately surrounding the blood vessels.