A forum dedicated to the expansion in neuropathology knowledge for students and practitioners alike.
Cerebral edema, or increased swelling in the brain, can occur as the result of numerous etiologies, such as infection, inflammation, metabolic derangement, or neoplastic processes. Typically the brain has an undulating contour featuring crests or bumps called gyri, and troughs or grooves, called sulci. The mass effect produced by cerebral edema results in pushing or... Continue Reading →
Dandy-Walker malformation, an uncommon brain abnormality that may be seen in isolation or in association with other congenital abnormalities of brain development, is characterized by an enlarged posterior fossa, agenesis or hypoplasia of the cerebellar vermis, and cystic dilatation of the fourth ventricle. In this case of a term infant with multiple congenital abnormalities, the superior most aspect of the... Continue Reading →
A lacunar infarct is a small infarction, or stroke, that is usually less than about 1 to 1.5 cm in size and typically occurs in deep cerebral structures (e.g. basal ganglia) of hypertensive or diabetic patients with small vessel disease of deep penetrating arteries (e.g. lenticulostriate arteries) . The gross impression of this brain, which belonged to... Continue Reading →
Adventures in Neuropathology 