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The World Health Organization Classification of Tumors of the CNS officially recognizes 13 different variants of meningioma, most of which are Grade 1 tumors that are potentially curable with complete resection. Chordoid meningioma is a rare subtype that accounts for less than 1% of all intracranial meningiomas. They are commonly composed of epithelioid tumor cells,... Continue Reading →
Glioblastomas are malignant astrocytomas that often show pseudopalisading necrosis, characterized by palisading of neoplastic cells along the edges of tumor necrosis. Gioblastomas are the most common malignant primary brain tumor.
Learn about basic histopathologic diagnosis of diffuse astrocytomas. https://www.youtube.com/watch?v=sm764936sIg&feature=share
Short segment on recognizing vascular proliferation in Glioblastomas. https://www.youtube.com/watch?v=UefxKiHxwzo
This image of a nerve root shows axons myelinated by oligodendroglial cells of the central nervous system (top of image) and Schwann cells of the peripheral nervous system (bottom of image) at a point of transition called the Obersteiner-Redlich zone.
Coronal section of a fetal brain, approximately 21 weeks gestational age, with edema. Notice how, unlike in adult brains, there is no apparent delineation between white matter and grey matter due to incomplete myelination of the immature brain.
A common histologic finding in ependymomas (shown here) are perivascular pseudo-rosettes characterized by neoplastic ependymal cell nuclei radiating outward from a blood vessel, which creates a pink zone of glial processes immediately surrounding the blood vessels.Â
Learn about the normal structures, layers and chambers of the human eye. https://www.youtube.com/watch?v=iZCVDtHHa7U&feature=share Subscribe to your Adventures in Neuropathology YouTube channel for more educational neuropathology content:Â Â Adventures in Neuropathology
Learn about the histopathologic diagnosis of the secretory variant of meningioma. https://youtu.be/UzUqHRPx1eo Subscribe to your Adventures in Neuropathology YouTube channel for more educational neuropathology content:Â Â Adventures in Neuropathology
Stemming from the Latin word "Pilos", meaning "resembling or composed of hair", pilocytic astrocytomas are named as such because of their long hair-like gliofibrillary processes (clear arrows) that stem off of slender bipolar nuclei (black arrows), which are best seen on smear preparation of fresh tissue (depicted here).
Adventures in Neuropathology 