Multiple Schwannomas in Neurofibromatosis Type II (NF2)

Schwannomas are typically sporadic lesions which stem from the Schwann cells that myelinate (or insulate) the peripheral nerves.  Patients with multiple schwannomas are more likely to have an associated familial tumor syndrome, such as Neurofibromatosis Type II (NF2). NF2 is a disorder in which a person inherits a defective gene, called NF2, that affects the merlin tumor suppressor protein thereby permiting growth of tumors such as schwannomas and meningiomas.  The patient depicted here has NF2  and multiple schwannomas arising from the nerve roots – where the peripheral and central parts of the nervous system join.

multiple schwannomas in nf2

For further study on this topic and others related to neuropathology and neuroanatomy,  the following books come highly recommended, and a small portion of the proceeds (or any Amazon purchase through these links) help with expenses of hosting this site:

                                           

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

Powered by WordPress.com.

Up ↑

%d bloggers like this: